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Price and Beard state that FIDELITY trial began in 2005 inferring that we tested an outdated or non contemporary intervention, but fail to provide any rationale for this argument. Without knowing their specific arguments, it is obviously difficult to fully address this criticism, but we would like to point out that FIDELITY actually started in October 2007 and to our knowledge, no evidence has since been published to question the validity of the treatment strategy used. Such possibility obviously exists.

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